Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Big effect

Ginseng cut cancer-related fatigue by a wide margin in a four-week trial — but the effect was measured in gastrointestinal cancer survivors, a clinical group that may not reflect general use.

This is one of the first rigorous trials to test ginseng for this specific pairing, so while the effect is unusually large (Cohen's d = -1.26), the evidence is still early and limited to a narrow population.

In a double-blind trial, gastrointestinal cancer survivors who took 250 mg of Panax ginseng extract daily for four weeks reported significantly less fatigue than those on placebo — a drop from 5.37 to 3.99 on a standard fatigue scale. The same study also found improvements in daily activity, walking, mood, and enjoyment of life, all without side effects. However, because this is among the first indexed studies on ginseng for fatigue in this specific group, the results should be seen as promising but not yet generalizable to healthier or different populations.

Where this fits in the evidence

This is among the first studies we've indexed on Ginseng for Reduced Fatigue — treat it as an early signal until more research accumulates.

The study

The effect of ginseng extract on fatigue in cancer survivors: a randomized double-blind clinical trial.

  • Randomized Controlled Trial (RCT)
  • 2026-03-16
  • Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.

Back to top