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Evidence-Based Supplement Research
Evidence-Based Supplement Research
New evidence

A systematic review of 134 patients suggests propolis mouthwash may reduce the severity of radiation-induced mouth sores — but the evidence is still early and based on a small number of studies.

This is the first solid signal that propolis could help with a painful side effect of head and neck cancer treatment, but with only 134 patients and no standard dosing, it's too soon to treat it as a proven remedy.

Propolis, especially as a mouthwash, was linked to less severe oral mucositis in patients undergoing radiotherapy for head and neck cancer. The review pooled data from 134 people, but the studies were small and not blinded, and the optimal dose remains unclear. Consider this an early clue, not a clinical recommendation.

Where this fits in the evidence

This is among the first studies we've indexed on Propolis for Reduced Oral Mucositis Severity — treat it as an early signal until more research accumulates.

The study

Propolis may reduce severity for radiotherapy-induced oral mucositis: a systematic review.

  • Systematic Review
  • n = 134
  • 2026
  • Brazilian journal of biology = Revista brasleira de biologia

This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.

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