New evidence
Red sage cut creatinine and multiple inflammation markers in 1,970 people with diabetic kidney disease — but this is the first meta-analysis on the pairing, so the picture is far from settled.
This is the first solid systematic review linking red sage (Salvia miltiorrhiza) to kidney protection in diabetics, but because the evidence is still early and the underlying 21 trials varied in quality, the result is promising — not definitive.
A meta-analysis pooling 21 randomized trials found that people with diabetic kidney disease who took red sage preparations had lower serum creatinine and fewer markers of inflammation (like CRP and TNF-α) compared to controls. The effect was statistically significant, but the analysis didn't specify the dose used, and since this is among the first studies to look at this combination, the results need replication before anyone should act on them.
Where this fits in the evidence
This is among the first studies we've indexed on Red Sage for Reduced Serum Creatinine Levels — treat it as an early signal until more research accumulates.
The study
- Systematic Review
- n = 1,970
- 2025-09-12
- Frontiers in pharmacology
This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.