Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In
Big effect

Vitamin C added to standard care sharply improved blood pressure and organ function in septic shock — but the result comes from a small, early study in critically ill patients.

This is an early signal that vitamin C might help stabilize blood pressure in septic shock, but the evidence is too thin to generalize beyond the ICU setting.

In a trial of 110 septic shock patients, those who received vitamin C alongside standard hydrocortisone therapy showed significantly greater improvements in mean arterial pressure, heart rate, and markers of inflammation and organ failure than those on hydrocortisone alone. The study measured many related outcomes, all of which improved more with vitamin C. However, these findings are preliminary and apply specifically to critically ill patients already receiving steroid treatment.

Where this fits in the evidence

This is among the first studies we've indexed on Vitamin C for Improved Mean Arterial Pressure — treat it as an early signal until more research accumulates.

The study

Prognostic value of T-lymphocyte subsets, lymphocyte-to-high-density lipoprotein ratio, interleukin 6, C-reactive protein and procalcitonin in patients with septic shock and effects of vitamin C on patients with septic shock.

  • Randomized Controlled Trial (RCT)
  • n = 110
  • 2026-01-01
  • Pakistan journal of pharmaceutical sciences
More on Vitamin CMore on Improved Mean Arterial Pressure

This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.

Back to top