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Evidence-Based Supplement Research
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New evidence

Vitamin D for at least three months lowered thyroid antibodies in autoimmune patients — but the benefit may depend on starting levels.

This meta-analysis is the first to pool evidence on vitamin D and thyroid antibodies, but with only 577 patients and a wide range of doses, the results are preliminary and need replication.

The analysis found that taking vitamin D for at least three months reduced levels of two antibodies that attack the thyroid in people with autoimmune thyroid disease. The effect was most noticeable in those who had low vitamin D to begin with. Because the studies varied widely in dose and design, it's too early to say exactly how much vitamin D is needed.

Where this fits in the evidence

This is among the first studies we've indexed on Vitamin D for Reduced Anti-Thyroid Peroxidase Antibody — treat it as an early signal until more research accumulates.

The study

The impacts of vitamin D supplementation on serum levels of thyroid autoantibodies in patients with autoimmune thyroid disease: a meta-analysis.

  • Meta-Analysis
  • n = 577
  • 2025-06-16
  • PeerJ
More on Vitamin DMore on Reduced Anti-Thyroid Peroxidase Antibody

This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.

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