Infant respiratory distress syndrome
Infant Respiratory Distress Syndrome (IRDS), also known as surfactant deficiency disorder (SDD) or hyaline membrane disease (HMD), is a common breathing disorder in premature infants caused by a lack of surfactant, a substance that keeps the lungs expanded, leading to lung collapse and difficulty breathing. This condition predominantly affects babies born before 28 weeks of pregnancy and may result from developmental insufficiency of surfactant production, structural immaturity of the lungs, neonatal infection, or genetic issues related to surfactant-associated proteins.
Health Outcomes
- Earlier Achievement of Full Feeding
- Improved Apgar Score
- Improved Arterial Oxygen Partial Pressure
- Improved Gas Exchange
- Improved Neonatal Health Outcomes
- Improved Oxygen Saturation
- Improved Oxygenation Index
- Improved Survival Free from Neurodisability
- Increased Neonatal Death
- Increased Risk of Necrotizing Enterocolitis Stage 2 or Higher
- Necrotizing Enterocolitis in Preterm Neonates
- No Impact on Infant Anthropometric Measurements
- Reduced Age at Full Postnatal Feeds
- Reduced Bronchopulmonary Dysplasia Incidence
- Reduced Bronchopulmonary Dysplasia Severity
- Reduced Composite Outcome of Sepsis, Necrotizing Enterocolitis, or Mortality
- Reduced Duration of Mechanical Ventilation
- Reduced Full Feeding Days
- Reduced Intraventricular Hemorrhage
- Reduced Milk Aspiration
- Reduced NICU Admission
- Reduced NICU Requirement
- Reduced Necrotizing Enterocolitis Stage II
- Reduced Need for Mechanical Ventilation
- Reduced Need for Oxygen Therapy
- Reduced Neonatal Death
- Reduced Neonatal Mortality
- Reduced Oxygen Dependency
- Reduced Oxygen Requirement
- Reduced Oxygen Saturation Decrease
- Reduced Oxygen Support Requirement
- Reduced Perinatal Mortality
- Reduced Retinopathy of Prematurity
- Reduced Time to Cessation of Oxygen Support
- Reduced Time to Initiate Oral Feeding
- Reduced Time to Reach Full Feeds