Klinefelter Syndrome

Klinefelter Syndrome (KS), also known as 47,XXY, is a common chromosomal disorder in males, characterized by the presence of an extra X chromosome, leading to symptoms such as infertility, small testes with reduced testosterone production, learning disabilities, and coordination issues. Named after endocrinologist Harry Klinefelter, who identified the condition in the 1940s, it affects approximately one to two per 1,000 live births and symptoms often become apparent during puberty.