Mitochondrial disease
Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction due to mutations in the mitochondrial genome or mitochondrial DNA. These diseases primarily impact the muscles and nervous system by impairing the mitochondria's ability to generate the energy (ATP) needed for cell functions.
Health Outcomes
- Activated Mitophagy Pathway
- Elevated 3-Hydroxyphenylpropionic Acid Levels
- Enhanced Autophagy
- Enhanced Mitochondrial Biogenesis
- Facilitated Mitophagy
- Improved Anaerobic Running Capacity
- Improved Ataxia
- Improved Ataxia Rating Scale Score
- Improved Cytochrome c Oxidase Level
- Improved Energy Metabolism
- Improved Energy System Modulation
- Improved Lactate Utilization
- Improved Mitochondrial Efficiency
- Improved Mitochondrial Function
- Improved Mitochondrial Respiratory Health
- Improved Multisystem Symptoms
- Improved Redox Potential
- Increased Anion Gap
- Increased Dicarboxylic Fatty Acid Level
- Increased Fat Utilization
- Increased Fumaric Acid Production
- Increased Functional Genes
- Increased Glutathione Disulfide Ratio
- Increased Humanin Level
- Increased Lactate Accumulation
- Increased Lactate Production
- Increased Medium-Chain Acylcarnitines
- Increased Mitochondrial Levels
- Increased Oxidative Stress Tolerance
- Increased Serine Level
- Increased Time to Ventilatory Threshold
- Increased Total L-Carnitine Level
- Preserved Membrane Integrity
- Preserved Wheel-Running Activity
- Promoted Oxidative Muscle Fiber Composition
- Reduced Carbohydrate Oxidation
- Reduced Coenzyme Q10 Level
- Reduced Core Temperature
- Reduced Heat Intolerance
- Reduced Lactate Accumulation
- Reduced Lactate Conversion
- Reduced N-acetylaspartate Level
- Reduced Whole-Body Lipid Levels