Mitochondrial disease
Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction due to mutations in the mitochondrial genome or mitochondrial DNA. These diseases primarily impact the muscles and nervous system by impairing the mitochondria's ability to generate the energy (ATP) needed for cell functions.
Health Outcomes
- Activated Mitophagy Pathway
- Elevated 3-Hydroxyphenylpropionic Acid Levels
- Enhanced Autophagy
- Enhanced Mitochondrial Biogenesis
- Facilitated Mitophagy
- Improved Ataxia
- Improved Energy Metabolism
- Improved Lactate Utilization
- Improved Mitochondrial Function
- Improved Multisystem Symptoms
- Increased Anion Gap
- Increased Blood Lactate Level
- Increased Dicarboxylic Fatty Acid Level
- Increased Fumaric Acid Production
- Increased Functional Genes
- Increased Glutathione Disulfide Ratio
- Increased Lactate Accumulation
- Increased Lactate Production
- Increased Medium-Chain Acylcarnitines
- Increased Mitochondrial Levels
- Increased Oxidative Stress Tolerance
- Increased Serine Level
- Increased Time to Ventilatory Threshold
- Preserved Membrane Integrity
- Preserved Wheel-Running Activity
- Promoted Oxidative Muscle Fiber Composition
- Reduced Carbohydrate Oxidation
- Reduced Heat Intolerance
- Reduced Lactate Accumulation
- Reduced Lactate Conversion
- Reduced Lactate Dehydrogenase Levels
- Reduced Lactate Level
- Reduced N-acetylaspartate Level
- Reduced Whole-Body Lipid Levels