Primary Biliary Cholangitis
Primary Biliary Cholangitis (PBC) is a chronic autoimmune disease that progressively destroys the small bile ducts in the liver, leading to the build-up of bile and toxins, which can cause liver scarring, fibrosis, and eventually cirrhosis. This results in bile ducts becoming injured, inflamed, and ultimately destroyed, impairing digestion and liver function.
Health Outcomes
- Achieved Histological Remission
- Altered Bile Acid Composition
- Altered Bile Acid Metabolism
- Attenuated Hepatic Disorders
- Decreased Conjugated Bile Acid Level
- Downregulated Complement System Activity
- Elevated Alkaline Phosphatase Levels
- Elevated Bile Acid Levels
- Elevated Hepatic Enzyme Levels
- Elevated Plasma Immunoglobulin M Levels
- Elevated Serum Globulin Levels
- Elevated Serum IgM Levels
- Enhanced Alkaline Phosphatase Activity
- Enhanced Bile Salt Resistance
- Enhanced Viability in Bile Conditions
- Improved Bile Salt Hydrophobicity
- Improved Child-Pugh Score
- Improved Hepatic Function
- Improved Liver Biomarkers
- Improved Liver Disease Biomarkers
- Improved Liver Enzyme Activity
- Improved Liver Enzyme Function
- Improved Liver Function
- Improved Liver Histology
- Improved Organ Histology
- Improved Tolerance to Bile Salts
- Increased Alkaline Phosphatase Activity in Skin Mucus
- Increased Alkaline Phosphatase Level
- Increased Aspartate Aminotransferase Concentration
- Increased Bile Acid Excretion
- Increased Bile Acid Synthesis
- Increased Bile Resistance
- Increased Bile Salt Tolerance
- Increased CD4-CD8 Ratio
- Increased Circulating Bile Acid Levels
- Increased Conjugated Bile Acid Levels
- Increased Deconjugated Bile Acid Level
- Increased Immunoglobulin M
- Increased Immunoglobulin M Levels
- Increased Plasma Deconjugated Bile Acids
- Increased Plasma GLDH
- Increased Serum Total Bile Acid Levels
- Increased Total Bile Acid Levels
- Increased Total Bile Acids
- Increased Unconjugated Bile Acid Levels
- Increased Unconjugated Bile Acids
- Liver Histopathological Damage
- Lowered Serum Levels of Liver Injury Markers
- Maintained Albumin Levels
- Maintained Safety with Repeated Oral Exposure
- Modified Hepatic Inflammatory Cell Pattern
- Modulated Bile Acid Profile in Ileum
- Modulated Immune Marker IFN-γ
- No Change in Fibrosis
- Preserved Liver Function
- Preserved Liver Structure
- Prevented Liver Fibrosis
- Prevented Liver Pathway Dysregulation
- Prolonged INR
- Reduced ALT Levels
- Reduced Abnormal Cholestasis-Related Liver Indices
- Reduced Abnormal Increase in Bilirubin
- Reduced Alanine Transaminase Activity
- Reduced Bile Acid Levels
- Reduced Bile Acid Synthesis
- Reduced Cholestatic Pattern of Liver Injury
- Reduced Cholic Acid Level
- Reduced Dimethyl Sulfide Level
- Reduced Fasting Conjugated Bile Acids
- Reduced Gamma-Glutamyl Transferase Levels
- Reduced Hepatic Damage Indices
- Reduced Hepatic Histological Injury
- Reduced Hepatic Inflammation
- Reduced Hepatic Inflammation Markers
- Reduced Hepatic Inflammation and Oxidative Stress
- Reduced Incidence of Abnormal Increase in Alkaline Phosphatase
- Reduced Incidence of Cholestasis
- Reduced Intestinal Cholesterol Absorption
- Reduced Lithocholic Acid Concentration
- Reduced Liver Biochemical Markers
- Reduced Liver Damage
- Reduced Liver Disease Progression
- Reduced Liver Fibrosis
- Reduced Liver Function
- Reduced Liver Function Indicators
- Reduced Liver Inflammation
- Reduced Liver Inflammation Fibrosis Score
- Reduced Liver Injury Marker
- Reduced Liver Stiffness
- Reduced P1NP Level
- Reduced Pathological Changes of Liver
- Reduced Plasma Vitamin K Levels
- Reduced Procollagen Type 1 N-terminal Propeptide Level
- Reduced Serum Alanine Aminotransferase Activity
- Reduced Serum Transaminase Levels
- Reduced Total Bile Acid Levels
- Regulated Liver Immune Homeostasis
- Regulated Liver Metabolite Levels
- Significant Histopathological Changes in Liver
- Stable Alanine Aminotransferase Levels
- Stable Fecal Deconjugated Bile Acid Levels