Scleroderma
Scleroderma is a group of autoimmune connective tissue diseases that lead to skin thickening and can affect blood vessels, muscles, and internal organs, with symptoms including stiff skin, fatigue, and poor blood flow to extremities. It can manifest as localized or systemic forms, with systemic varieties such as CREST syndrome causing more widespread organ involvement and specific symptoms like calcium deposits and Raynaud's phenomenon.
Health Outcomes
- Altered Systemic Immune Response
- Improved Collagen Homeostasis
- Improved Connective Tissue Attachment Levels
- Improved Dry Eye Symptoms
- Improved Fibrosis
- Improved Immune-Related Symptoms
- Improved Stiffness
- Improved Tissue Pathology
- Increased Clinically Meaningful Collagen Synthesis
- Increased Collagen Content
- Increased Collagen Synthesis
- Increased Gastric Antral Length
- Increased Hyaluronic Acid Synthesis in Fibroblasts
- Increased Risk of Gastroesophageal Reflux Disease
- Increased Skin Thickness
- Increased T Cell Activation
- Increased Type 1 Collagen Synthesis
- Inhibited Autoimmune Activation
- Maintained Epithelium Structure
- Modulated Humoral Inflammation
- No Change in Fibrosis
- Reduced Debridement Time
- Reduced Duodenal Pressure
- Reduced Gastric Emptying
- Reduced Pro-Inflammatory Immune Activity
- Reduced Prostaglandin E2 Level
- Reduced Skin Dryness Symptoms
- Reduced Skin Oiliness
- Reduced Wound Area
- Regressed Esophagitis