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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Increased 25-hydroxyvitamin D Level

Ranked by research evidence. Compare 3 supplements across 7 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • High evidence5 studies

    Across all 5 studies, 5 reported beneficial effects on increased 25-hydroxyvitamin D levels, all statistically significant. The predominant effect size is moderate, with one study reporting a large effect. The median study duration was 90 days, indicating effects are typically observed at 8-12 weeks. The most-studied populations include older adults, healthy children, and clinical populations (Parkinson's disease, lupus, multiple sclerosis).

    Dose: 1000-7000 IU/day (weekly dosing up to 100,000 IU used in one high-dose study)
    Product match
    Viva NaturalsVitamin D3 with Organic Liquid Coconut Oil
    125 mcg · $15.16 · ★5.0 (208)
3 supplements
  • HighVitamin DAcross all 5 studies, 5 reported beneficial effects on increased 25-hydroxyvitamin D levels, all statistically significant. The predominant effect size is moderate, with one study reporting a large effect. The median study duration was 90 days, indicating effects are typically observed at 8-12 weeks. The most-studied populations include older adults, healthy children, and clinical populations (Parkinson's disease, lupus, multiple sclerosis). · Dose: 1000-7000 IU/day (weekly dosing up to 100,000 IU used in one high-dose study)5 beneficial5 studies
  • Vitamin D31 beneficial1 study
  • Vitamin D21 beneficial1 study
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