Best Supplements for Increased Folate Level
Ranked by research evidence. Compare 3 supplements across 5 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence3 studies
Across 3 studies, 2 reported beneficial effects (one large, one moderate-to-large) and 1 reported a neutral effect. Two of the three studies found statistically significant increases in folate levels, with the largest effect observed in a meta-analysis of patients with phenylketonuria (SMD: 1.378). The median study duration among the one study that reported it was 84 days (12 weeks), suggesting effects are typically observed at that timepoint. Doses and forms were not consistently reported across studies.
3 supplements
- LowVitamin B9Across 3 studies, 2 reported beneficial effects (one large, one moderate-to-large) and 1 reported a neutral effect. Two of the three studies found statistically significant increases in folate levels, with the largest effect observed in a meta-analysis of patients with phenylketonuria (SMD: 1.378). The median study duration among the one study that reported it was 84 days (12 weeks), suggesting effects are typically observed at that timepoint. Doses and forms were not consistently reported across studies.2 beneficial1 neutral3 studies