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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Increased Lean Mass

Ranked by research evidence. Compare 12 supplements across 17 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence3 studies

    Across 3 studies, 1 reported a beneficial moderate-sized effect on increased lean mass (45 g/day in young untrained males), while 2 reported neutral small effects (including a large meta-analysis in older adults). Median study duration was 84 days. The overall evidence is mixed, with no consistent effect across populations.

    Product match
    Mason NaturalFolic Acid
    · $3.12 · ★4.8 (2,708)
12 supplements
  • LowWhey ProteinAcross 3 studies, 1 reported a beneficial moderate-sized effect on increased lean mass (45 g/day in young untrained males), while 2 reported neutral small effects (including a large meta-analysis in older adults). Median study duration was 84 days. The overall evidence is mixed, with no consistent effect across populations.1 beneficial2 neutral3 studies
  • Soy Protein1 beneficial1 neutral2 studies
  • Calcium1 beneficial1 study
  • Zinc1 beneficial1 study
  • Selenium1 beneficial1 study
  • Iron1 beneficial1 study
  • Vitamin C1 beneficial1 study
  • Vitamin E1 beneficial1 study
  • L-Citrulline2 neutral2 studies
  • Beta-Alanine2 neutral2 studies
  • Milk Protein1 neutral1 study
  • Casein Protein1 neutral1 study
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