Best Supplements for Reduced Complex Regional Pain Syndrome
Ranked by research evidence. Compare 1 supplement across 3 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence3 studies
Across 3 studies, all reported beneficial small-sized effects of vitamin C supplementation for reducing complex regional pain syndrome (CRPS), with all findings statistically significant. The evidence is strongest and most consistent in surgical populations (total knee arthroplasty), where doses of 1 g daily for approximately 40 days were associated with reduced CRPS incidence (odds ratio 0.59 in one study). Effects were typically observed at around 40 days.
Dose: 1 g daily
1 supplement
- ModerateVitamin CAcross 3 studies, all reported beneficial small-sized effects of vitamin C supplementation for reducing complex regional pain syndrome (CRPS), with all findings statistically significant. The evidence is strongest and most consistent in surgical populations (total knee arthroplasty), where doses of 1 g daily for approximately 40 days were associated with reduced CRPS incidence (odds ratio 0.59 in one study). Effects were typically observed at around 40 days. · Dose: 1 g daily3 beneficial3 studies