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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Duration of Hospitalization

Ranked by research evidence. Compare 2 supplements across 4 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Moderate evidence3 studies

    Across 3 studies, all 3 reported beneficial effects of Lactobacillus reuteri DSM 17938 on reducing hospitalization duration, with predominantly small to moderate effect sizes. The evidence comes primarily from children with acute gastroenteritis, where a meta-analysis of 3 RCTs (n=284) found a small reduction of 0.54 days (95% CI [-1.09, 0.0]), and one RCT in children under 5 showed a significant benefit. A systematic review in preterm neonates reported a larger reduction of 10.77 days, but this finding is from older, smaller trials. Doses and study durations were inconsistently reported.

2 supplements
  • ModerateLactobacillus reuteri DSM 17938Across 3 studies, all 3 reported beneficial effects of Lactobacillus reuteri DSM 17938 on reducing hospitalization duration, with predominantly small to moderate effect sizes. The evidence comes primarily from children with acute gastroenteritis, where a meta-analysis of 3 RCTs (n=284) found a small reduction of 0.54 days (95% CI [-1.09, 0.0]), and one RCT in children under 5 showed a significant benefit. A systematic review in preterm neonates reported a larger reduction of 10.77 days, but this finding is from older, smaller trials. Doses and study durations were inconsistently reported.3 beneficial3 studies
  • N-Acetyl Cysteine1 neutral1 study
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