Aloe and Reduced Hand Foot Syndrome Severity

• A Randomized Single-Blinded Phase II Trial Comparing Efficacy and Quality of Life of Topical Aloe Vera Gel Plus Urea Cream Versus Urea Cream Alone for Prevention of Hand Foot Syndrome in Cancer Patients Receiving Capecitabine.

  • 2024-06-01
  • RCT · n = 31
  • Asian Pacific journal of cancer prevention : APJCP 25(6)
  • • Lucksika Wanichtanom
    • Gorn Vrakornvoravuti
    • Metavee Boonsiri
    • Apisada Suthepwanon

  • PubMed: 38918684
  • DOI: 10.31557/apjcp.2024.25.6.2203

  2 Insights on

  • Reduced Hand Foot Syndrome Severity

  • High evidence
  • Clinical

  Grade 2-3 HFS was significantly lower in the combination group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes