Anthocyanins and Reduced Risk of Digestive System Cancer

• Unravelling the Link between Polyphenol Intake and the Risk of Digestive System Cancer: An Umbrella Review Using Meta-Analyses and Systematic Reviews.

  • 2026
  • Systematic Review
  • Expert reviews in molecular medicine 28
  • • Arezo Amjadi
    • Hamid Abbasi
    • Atefeh Tahavorgar
    • Mohammadreza Esfahanian
    • Mahdie Torkaman
    • Adel Shahrokhi Sardoo
    • Ali Erfanimanesh
    • Ali Shamsi-Goushki
    • Mohammad Esmail Akbari
    • Barbod Alhouei
    • Maryam Gholamalizadeh
    • Saeid Doaei

  • PubMed: 41502351
  • DOI: 10.1017/erm.2025.10027

  1 Insight on

  • Reduced Risk of Digestive System Cancer

  • High evidence

  Subgroup analysis revealed significant risk reductions for specific polyphenol classes: flavonols (22%), quercetin (22%), anthocyanidins (16%), flavan-3-ols (12%) and isoflavones (9%).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes