Research synthesisModerate evidenceMixed effect size3 studies · 3 beneficial · 0 neutral · 0 harmful
Across 3 studies, all reported beneficial effects on sleep quality. Effect sizes were mixed (small to large). The most studied dose range was 120-1000 mg/day, with median study duration of 56 days. Populations included healthy individuals and those with stress-related or clinical conditions (anxiety, insomnia, mental disorders).
- Effective dose range: 120-1000 mg/day
- Studied populations: healthy individuals and patients with stress-related or functional disorders, anxiety/insomnia, or mental disorders
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Effect sizes varied substantially across studies (small to large).
Generated May 15, 2026