Bacopa and Improved Cognitive Function

Doses used in studies

mg/day: 160 (median 160, IQR 160–160) — 1 study

Time to effect

Median: 8.6 weeks · IQR 8.6 weeks–8.6 weeks · Range 8.6 weeks–8.6 weeks — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.
- 2024-03-03
- RCT · n = 62
- Explore (New York, N.Y.) 20(5)
- - Maryam Delfan
  - Parastou Kordestani-Moghaddam
  - Mohammad Gholami
  - Khadije Kazemi
  - Rasool Mohammadi
- PubMed: 38538390
- DOI: 10.1016/j.explore.2024.02.008
4 Insights on
- Improved Cognitive Function
- High evidence
- Clinical
The results showed no statistically significant difference between two groups in all three time-points in overall cognitive performance score and its 6 parameters (P > 0.05). While in the field of attention at the end of the first month (P = 0.033) and the end of the second month (P = 0.004), it was significant difference between the study groups. Also, in the field of verbal fluency at the end of the second month, this difference was significant (P = 0.003). The cognitive performance overall score showed no significant difference between two groups in first (P = 0.939) and second time-points (P = 0.661), although it was significant at third time-point (P = 0.029).
Effect
Neutral
Effect size
Small
Significant
No
Dose
160 mg/day
Investigating the Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review Focused on Inflammation, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis.
- 2024-03-25
- Review
- Antioxidants (Basel, Switzerland) 13(4)
- - Luiz José Valotto Neto
  - Matheus Reverete de Araujo
  - Renato Cesar Moretti Junior
  - Nathalia Mendes Machado
  - Rakesh Kumar Joshi
  - Daiene Dos Santos Buglio
  - Caroline Barbalho Lamas
  - Rosa Direito
  - Lucas Fornari Laurindo
  - Masaru Tanaka
  - Sandra Maria Barbalho
- PubMed: 38671841
- DOI: 10.3390/antiox13040393
14 Insights on
- Improved Cognitive Function
- Low evidence
BM can reduce Nuclear Factor-κB phosphorylation, improve emotional function, cognitive functions, anhedonia, hyperactivity, sleep routine, depression, attention deficit, learning problems, memory retention, impulsivity, and psychiatric problems.
Effect
Beneficial
Effect size
Small
Significant
Yes

Bacopa and Improved Cognitive Function

Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.

Investigating the Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review Focused on Inflammation, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis.