Bitter Melon and Improved Fasting Plasma Glucose

• Momordica charantia L. lowers elevated glycaemia in type 2 diabetes mellitus patients: Systematic review and meta-analysis.

  • 2019-03
  • Meta-Analysis · n = 1,045
  • Journal of ethnopharmacology 231
  • • Emanuel L Peter
    • Félicien Mushagalusa Kasali
    • Serawit Deyno
    • Andrew Mtewa
    • Prakash B Nagendrappa
    • Casim Umba Tolo
    • Patrick Engeu Ogwang
    • Duncan Sesaazi

  • PubMed: 30385422
  • DOI: 10.1016/j.jep.2018.10.033

  3 Insights on

  • Improved Fasting Plasma Glucose

  • High evidence
  • Clinical

  M. charantia also lowered FPG in prediabetes (mean difference -0.31 mmol/L, n=52); the evidence was downgraded to low quality because the study had unclear risk of bias and inadequate sample size.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Phytotherapeutic Supplementation with Momordica charantia: Beneficial Effects in Patients with Suboptimal Glycemic Control on Double Antidiabetic Therapy-A Real-World Evidence Observational Study.

  • 2026-01-19
  • Observational · n = 85
  • Nutrients 18(2)
  • • Cosmin Mihai Vesa
    • Timea Claudia Ghitea
    • Ada Radu
    • Andrei Flavius Radu
    • Teodora Maria Bodog
    • Ruxandra Florina Bodog
    • Roxana Daniela Brata
    • Cristiana Bustea

  • PubMed: 41599921
  • DOI: 10.3390/nu18020309

  2 Insights on

  • Improved Fasting Plasma Glucose

  • High evidence
  • Rigorous Journal
  • Clinical

  Fasting plasma glucose declined from 138.4 ± 17.5 mg/dL at baseline to 122.3 ± 13.1 mg/dL at 6 months and to 113.3 ± 12.2 mg/dL at 9 months in the intervention group

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  standardized extract (dose not specified in abstract)