Efficacy and safety of oral Nigella sativa oil for symptomatic treatment of knee osteoarthritis: A double-blind, randomized, placebo-controlled clinical trial.
- 2022-11
- RCT · n = 58
- Complementary therapies in clinical practice 49
- Hasan Fallah Huseini
- Reza Mohtashami
- Elaheh Sadeghzadeh
- Soraya Shadmanfar
- Fataneh Hashem-Dabaghian
- Saeed Kianbakht
- PubMed: 36150238
- DOI: 10.1016/j.ctcp.2022.101666
- High evidence
- Clinical
WOMAC total scores were decreased by 27.72 ± 18.61% (NS oil group) and 1.34 ± 2.31% (placebo group) (p < 0.001)
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 2.5 mL every 8 hours