Black Cumin and Reduced Intercellular Adhesion Molecule-1 Level

Doses used in studies

g/day: 2 (median 2, IQR 2–2) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

Efficacy of nigella sativa oil on endothelial function and atherogenic indices in patients with coronary artery diseases: A randomized, double-blind, placebo-control clinical trial.

2022-07-24
RCT
Phytotherapy research : PTR 36(12)
- Omid Mohammad Tavakoli-Rouzbehani
- Mohsen Abbasnezhad
- Sorayya Kheirouri
- Mohammad Alizadeh

PubMed: 35871718
DOI: 10.1002/ptr.7568

4 Insights on

Reduced Intercellular Adhesion Molecule-1 Level

High evidence
Clinical

Serum levels of vascular cell adhesion protein 1 (sVCAM-1) [-264.44 95% C, (156.83, 372.04)], intercellular adhesion molecule 1 (sICAM-1) [-132.38 95% C, (40.64, 224.1)], and malondialdehyde (MDA) [-0.21 95% C, (0.03, 0.40)] declined significantly following NS supplementation, while total antioxidant capacity increased [0.03 95% C, (0.03, 0.16)].

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: 2 g/daily