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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Black Cumin and Reduced Interleukin-1β mRNA Expression

Doses used in studies

mg/day: 2,000 (median 2,000, IQR 2,000–2,000) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

A crossover randomized controlled trial examining the effects of black seed (Nigella sativa) supplementation on IL-1β, IL-6 and leptin, and insulin parameters in overweight and obese women.
- 2024-01-05
- RCT
- BMC complementary medicine and therapies 24(1)
- - Elham Razmpoosh
  - Sara Safi
  - Mahta Mazaheri
  - Saman Khalesi
  - Majid Nazari
  - Parvin Mirmiran
  - Azadeh Nadjarzadeh
- PubMed: 38178093
- DOI: 10.1186/s12906-023-04226-y
6 Insights on
- Reduced Interleukin-1β mRNA Expression
- High evidence
- Clinical
NS supplementation significantly reduced the mRNA expressions(d=-0.68, P = 0.03)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
2000 mg/day