Black Cumin and Reduced Leptin Levels

Doses used in studies

mg/day: 2,000 (median 2,000, IQR 2,000–2,000) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

A crossover randomized controlled trial examining the effects of black seed (Nigella sativa) supplementation on IL-1β, IL-6 and leptin, and insulin parameters in overweight and obese women.

2024-01-05
RCT
BMC complementary medicine and therapies 24(1)
- Elham Razmpoosh
- Sara Safi
- Mahta Mazaheri
- Saman Khalesi
- Majid Nazari
- Parvin Mirmiran
- Azadeh Nadjarzadeh

PubMed: 38178093
DOI: 10.1186/s12906-023-04226-y

6 Insights on

Reduced Leptin Levels

High evidence
Clinical

and Leptin(d=-1.9, d=-0.89, respectively; P < 0.01, serum leptin P carryover < 0.001). Despite the meaningful carryover effect for serum leptin, results remained significant following the first intervention period analysis(P < 0.001).

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 2000 mg/day