Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled trial.
- 2025-11
- RCT · n = 442
- The American journal of clinical nutrition 122(5)
- Xiaoran Liu
- Frank M Sacks
- Todd Beck
- Christy C Tangney
- Walter C Willett
- Hussein Yassine
- Klodian Dhana
- Neelum T Aggarwal
- Kumar B Rajan
- Lisa L Barnes
- PubMed: 40876538
- DOI: 10.1016/j.ajcnut.2025.08.012
- High evidence
- Large Human Trial
- Clinical
Associations in noncarriers were weaker or nonsignificant.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No