Calendula and Reduced Prevalence of Radiation-Induced Dermatitis

• Efficacy of topical Calendula officinalis on prevalence of radiation-induced dermatitis: A randomised controlled trial.

  • 2020-09-23
  • RCT · n = 271
  • The Australasian journal of dermatology 62(1)
  • • Shihab Siddiquee
    • Margaret A McGee
    • Andrew D Vincent
    • Eileen Giles
    • Robyn Clothier
    • Scott Carruthers
    • Michael Penniment

  • PubMed: 32965030
  • DOI: 10.1111/ajd.13434

  1 Insight on

  • Reduced Prevalence of Radiation-Induced Dermatitis

  • High evidence
  • Large Human Trial
  • Clinical

  There was no detectable difference in prevalence of radiation-induced dermatitis grade 2+ between the Calendula (53%) and Sorbolene (62%) groups (primary analysis OR = 0.87, 95% CI: [0.36, 2.09], P = 0.92; covariate adjusted complete case analysis OR 0.40, 95% CI: [0.13, 1.20], P = 0.10).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No