California Poppy and Reduced Anxiety

Time to effect

Median: 3 months · IQR 3 months–3 months · Range 3 months–3 months — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported11.5% vs 9.7%
In all, 15 patients (11.5%) in the study drug group and 13 patients (9.7%) in the placebo group experienced 22 and 15 adverse events, respectively. Undesirable events were mainly mild or moderate digestive or psychopathological disorders.
from: Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of

1 of 1 paper

Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders.

2003-10-20
RCT · n = 264
Current medical research and opinion 20(1)
- Michel Hanus
- Jacqueline Lafon
- Marc Mathieu

PubMed: 14741074
DOI: 10.1185/030079903125002603

2 Insights on

Reduced Anxiety

High evidence
Large Human Trial
Clinical

Total and somatic Hamilton scale scores and subjective patient-rated anxiety fell during treatment, indicating clinical improvement. The decrease was greater in the study drug than in the placebo group. End of treatment clinical improvement, as measured by the mean difference between final and pre-treatment scores, was, for the study drug and placebo groups respectively: -38.5 and -29.2 for subjectively assessed anxiety (p = 0.005)

Effect: Beneficial
Effect size: Large
Significant: Yes