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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Cat's Claw and Reduced Knee Circumference

Time to effect

Median: 4 weeks · IQR 4 weeks–4 weeks · Range 4 weeks–4 weeks — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityNo significant difference
Cat's claw had no deleterious effects on blood or liver function or other significant side-effects compared to placebo.
from: Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms o

1 of 1 paper

Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis.
- 2001-09
- RCT
- Inflammation research : official journal of the European Histamine Research Society ... [et al.] 50(9)
- - J Piscoya
  - Z Rodriguez
  - S A Bustamante
  - N N Okuhama
  - M J Miller
  - M Sandoval
- PubMed: 11603848
- DOI: 10.1007/pl00000268
5 Insights on
- Reduced Knee Circumference
- High evidence
- Clinical
Knee pain at rest or at night, and knee circumference were not significantly reduced by cat's claw during this brief trial.
Effect
Neutral
Effect size
Small
Significant
No