Use of Vitex agnus-castus in migrainous women with premenstrual syndrome: an open-label clinical observation.
- 2012-07-12
- Clinical Trial · n = 107
- Acta neurologica Belgica 113(1)
- Anna Ambrosini
- Cherubino Di Lorenzo
- Gianluca Coppola
- Francesco Pierelli
- PubMed: 22791378
- DOI: 10.1007/s13760-012-0111-4
- High evidence
- Large Human Trial
- Clinical
57 % of patients experienced a reduction higher than 50 % in monthly days with headache
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 40 mg/day