Chebulic Myrobalan and Reduced Depressive Symptom

Doses used in studies

mg/day: 3,000 (median 3,000, IQR 3,000–3,000) — 1 study

Time to effect

Median: 4 weeks · IQR 4 weeks–4 weeks · Range 4 weeks–4 weeks — Reported in 1 of 1 study

1 of 1 paper

Evaluating the effect of black myrobalan on cognitive, positive, and negative symptoms in patients with chronic schizophrenia: A randomized, double-blind, placebo-controlled trial.

2021-11-23
RCT
Phytotherapy research : PTR 36(1)
- Mohammad Banazadeh
- Mitra Mehrabani
- Nabi Banazadeh
- Fatemeh Dabaghzadeh
- Farzad Shahabi

PubMed: 34814232
DOI: 10.1002/ptr.7340

5 Insights on

Reduced Depressive Symptom

High evidence
Clinical

Patients' cognitive impairments, positive, negative, depression/anxiety, and excitement/activity symptoms were assessed ... Cognitive impairments (SCIP) ... negative symptoms ... and excitement/activity ... were significantly improved ... (no significant effect reported for depression/anxiety symptoms)

Effect: Neutral
Effect size: Small
Significant: No
Dose: 3000 mg/day (six 500 mg capsules in two divided doses)