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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Cocoa and Improved Episodic Memory

Doses used in studies

mg/day: 500 (median 500, IQR 500–500) — 1 study

Time to effect

Median: 24.3 months · IQR 24.3 months–24.3 months · Range 24.3 months–24.3 months — Reported in 1 of 1 study

1 of 1 paper

Effect of cocoa extract supplementation on cognitive function: results from the clinic subcohort of the COSMOS trial.
- 2024-01
- Clinical Trial · n = 573
- The American journal of clinical nutrition 119(1)
- - Chirag M Vyas
  - JoAnn E Manson
  - Howard D Sesso
  - Pamela M Rist
  - Alison Weinberg
  - Eunjung Kim
  - M Vinayaga Moorthy
  - Nancy R Cook
  - Olivia I Okereke
- PubMed: 38070683
- DOI: 10.1016/j.ajcnut.2023.10.031
3 Insights on
- Improved Episodic Memory
- High evidence
- Large Human Trial
- Mixed
CE, compared with placebo, had no significant effects on 2-y change in episodic memory [mean difference (95% CI): -0.01 (-0.13, 0.10) SU]
Effect
Neutral
Effect size
Small
Significant
No
Dose
500 mg flavanols/d, including 80 mg (-)-epicatechin