Cocoa and Improved Global Cognition

Doses used in studies

mg/day: 500 (median 500, IQR 500–500) — 1 study

Time to effect

Median: 24.3 months · IQR 24.3 months–24.3 months · Range 24.3 months–24.3 months — Reported in 1 of 1 study

1 of 1 paper

Effect of cocoa extract supplementation on cognitive function: results from the clinic subcohort of the COSMOS trial.

2024-01
Clinical Trial · n = 573
The American journal of clinical nutrition 119(1)
- Chirag M Vyas
- JoAnn E Manson
- Howard D Sesso
- Pamela M Rist
- Alison Weinberg
- Eunjung Kim
- M Vinayaga Moorthy
- Nancy R Cook
- Olivia I Okereke

PubMed: 38070683
DOI: 10.1016/j.ajcnut.2023.10.031

3 Insights on

Improved Global Cognition

High evidence
Large Human Trial
Mixed

Daily supplementation with CE, compared with placebo, had no significant effect on 2-y change in global cognition {mean difference [95% confidence interval (CI)]: -0.01 (-0.08, 0.05) standard deviation units (SU)}.

Effect: Neutral
Effect size: Small
Significant: No
Dose: 500 mg flavanols/d, including 80 mg (-)-epicatechin