The role of cocoa flavanols in modulating peripheral and cerebral microvascular function in healthy individuals and populations at-risk of cardiovascular disease: a systematic review.
- 2025-04-11
- Systematic Review · n = 13
- Nutrition journal 24(1)
- Sophie Richardson
- Janice Marshall
- Catarina Rendeiro
- PubMed: 40217225
- DOI: 10.1186/s12937-025-01121-9
- High evidence
- Clinical
For chronic studies (n = 7), the effect of CFs was less clear, with a significant benefit reported at rest only, in all young, healthy subgroups... but no evidence of improvements in vasodilator responses.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No