Cocoa and Reduced Incident Hypertension

Doses used in studies

With Epicatechin · mg/day: 500 (median 500, IQR 500–500) — 1 study

Time to effect

Median: 41.4 months · IQR 41.4 months–41.4 months · Range 41.4 months–41.4 months — Reported in 1 of 1 study

1 of 1 paper

Long-Term Effect of Cocoa Extract Supplementation on Incident Hypertension.

2025-10
RCT · n = 442
Hypertension (Dallas, Tex. : 1979) 82(10)
- Rikuta Hamaya
- Sidong Li
- Jessica Lau
- Matthew Allison
- Bernhard Haring
- Aladdin H Shadyab
- Nudy Matthew
- Lisa Warsinger Martin
- Pamela M Rist
- JoAnn E Manson
- Howard D Sesso

PubMed: 40832703
DOI: 10.1161/hypertensionaha.125.25209

1 Insight on

Reduced Incident Hypertension

High evidence
Large Human Trial
Elderly

cocoa extract supplementation reduced the incidence of hypertension among participants with baseline systolic BP <120 mm Hg (hazard ratio, 0.76 [0.64-0.90])

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 500 mg/d cocoa flavanols, with 80 mg/d (-)-epicatechin