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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Coconut and Reduced Tumor Necrosis Factor Alpha

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 1 study

1 of 1 paper

Anti-inflammatory and antimicrobial efficacy of coconut oil for periodontal pathogens: a triple-blind randomized clinical trial.
- 2025-03-14
- RCT · n = 30
- Clinical oral investigations 29(4)
- - Simón Pardiñas López
  - Mónica E García-Caro
  - Juan A Vallejo
  - Pablo Aja-Macaya
  - Kelly Conde-Pérez
  - Paula Nión-Cabeza
  - Ismael Khouly
  - Germán Bou
  - Ana Isabel Rodríguez Cendal
  - Silvia Díaz-Prado
  - Margarita Poza
- PubMed: 40085302
- DOI: 10.1007/s00784-025-06267-8
5 Insights on
- Reduced Tumor Necrosis Factor Alpha
- High evidence
- Clinical
the coconut oil demonstrated a reduction in IL-6 and TNF-α levels, indicating decreased local inflammation.
Effect
Beneficial
Effect size
Moderate
Significant
Yes