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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Echinacea and Reduced Antibiotic Use

Doses used in studies

mg/day: 2,000 (median 2,000, IQR 2,000–2,000) — 1 study

Safety in these studies

Overall tolerabilityIncreased riskRR = 1.38, 95 % CI [1.08; 1.78]
adverse events were moderately increased (RR = 1.38, 95 % CI [1.08; 1.78])
from: Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and com
Overall tolerabilityReported
though generally mild
from: Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and com

2 of 2 papersPopulation:

Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis media in children: Systematic review and meta-analysis.
- 2025-06
- Meta-Analysis · n = 1,651
- Clinical nutrition ESPEN 67
- - Thi-Phuong-Thao Pham
  - Thi-Mai-Hoa Vu
  - Pham-Minh-Khue Doan
  - Thi-Thuy-Duong Nguyen
  - Thi-Thu-Thuy Bui
  - Thi-Hong-Linh Ha
  - Thi-Kim-Quy Hoang
  - Indra Putra Taufani
  - Hai-Anh Ha
- PubMed: 40311928
- DOI: 10.1016/j.clnesp.2025.04.025
5 Insights on
- Reduced Antibiotic Use
- High evidence
E. purpurea significantly benefits URTI, reducing ... antibiotic use (RR = 0.18, 95 % CI [0.13; 0.25], p < 0.01)
Effect
Beneficial
Effect size
Large
Significant
Yes
Role of Echinacea in the management and prevention of acute respiratory tract infections in children: A systematic review of the evidence.
- 2025-10
- Review
- Journal of family & community medicine 32(4)
- - Ahlam Mazi
  - Reem M Alqahtani
- PubMed: 41234257
- DOI: 10.4103/jfcm.jfcm_144_25
6 Insights on
- Reduced Antibiotic Use
- Low evidence
- Children
Grading of recommendations assessment, development, and evaluation assessment indicated high certainty of the reduction of symptom duration and antibiotic use
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
not stated