Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
- 2024-06-14
- RCT · n = 119
- Medicine 103(24)
- Wankiun Lee
- Manho Kim
- PubMed: 38875437
- DOI: 10.1097/md.0000000000038067
- High evidence
- Large Human Trial
- Clinical
Combination group (DA+DG) not shown to improve ADAS-Cog; only DN group showed significant improvement.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- not stated