Transient Mood Elevation Without a Manic Switch: Goldenseal-Augmented Oral Glutamatergic Regimen in Bipolar Depression With Comorbid Obsessive-Compulsive Disorder (OCD).
- 2026-02-24
- Case Report
- Cureus 18(2)
- Ngo Cheung
- PubMed: 41756342
- DOI: 10.7759/cureus.104209
- Low evidence
Ten days after he added 600 mg of the herbal CYP2D6 inhibitor goldenseal, thought to slow the breakdown of dextromethorphan, he reported a clear lift in energy, mood, and work performance, with no signs of hypomania
- Effect
- Beneficial
- Effect size
- Moderate
- Dose
- 600 mg