Grape and Reduced Leg Circumference

• Vitis Vinifera Seed Extract Versus Micronized Purified Flavonoid Fraction for Patients with Chronic Venous Disease: A Randomized Noninferiority Trial.

  • 2024-12
  • RCT · n = 303
  • Annals of vascular surgery 109
  • • Suh Min Kim
    • Jin Hyun Joh
    • In Mok Jung
    • Mi Jin Kim
    • Sang Su Lee
    • Hong Pil Hwang
    • Jin Mo Kang
    • Hyuk Jae Jung
    • Shin-Seok Yang
    • Seung-Kee Min
    • Young Sun Yoo
    • Jun Gyo Gwon
    • Hyung Sub Park
    • Taeseung Lee

  • PubMed: 39009117
  • DOI: 10.1016/j.avsg.2024.06.011

  4 Insights on

  • Reduced Leg Circumference

  • High evidence
  • Large Human Trial
  • Clinical

  The calf circumference measured at 8 weeks was significantly reduced compared to that at baseline in patients receiving Vitis vinifera seed extract.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  not specified in abstract