Grapefruit and Reduced Salivary Nitrite Level

• Grapefruit juice enhances the systolic blood pressure-lowering effects of dietary nitrate-containing beetroot juice.

  • 2020-07-09
  • RCT
  • British journal of clinical pharmacology 87(2)
  • • Kevin O'Gallagher
    • Sarah Borg Cardona
    • Callum Hill
    • Ali Al-Saedi
    • Fawzia Shahed
    • Christopher N Floyd
    • Karen McNeill
    • Charlotte E Mills
    • Andrew J Webb

  • PubMed: 32520418
  • DOI: 10.1111/bcp.14420

  6 Insights on

  • Reduced Salivary Nitrite Level

  • High evidence
  • Adults

  as was salivary nitrite production (P = .002) and saliva volume (-0.34 mL/min [95% CI -0.05 to -0.68])

  Effect

  Harmful

  Effect size

  Small

  Significant

  Yes

  Dose

  250 mL