The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- 2025-08-27
- RCT · n = 30
- Nutrients 17(17)
- Shuqi Li
- Clarinda Nataria Sutanto
- Xuejuan Xia
- Jung Eun Kim
- PubMed: 40944161
- DOI: 10.3390/nu17172773
- High evidence
- Rigorous Journal
- Elderly
A significant time effect was observed in the MoCA score, which was mainly explained by a significant increase in the 5-HTP group (week 0 vs. week 12: 26.6 ± 1.4 a.u. vs. 27.6 ± 1.4 a.u., p < 0.05).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- 100 mg/day