Griffonia and Increased Mechanical Allodynia Distance

• The Effect of Griffonia simplicifolia on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volunteers-A Randomized, Double-Blinded, Placebo-Controlled Crossover Trial.

  • 2026-05-19
  • RCT · n = 17
  • Nutrients 18(10)
  • • Anselm Johannes Schlemmer
    • Sascha Hammer
    • Simon Fandler-Höfler
    • Kordula Lang-Illievich
    • Helmar Bornemann-Cimenti

  • PubMed: 42197069
  • DOI: 10.3390/nu18101609

  9 Insights on

  • Increased Mechanical Allodynia Distance

  • High evidence
  • Rigorous Journal
  • Adults

  The only significant difference was an increased distance of mechanical allodynia in the verum group (β = 0.82; 95% CI 0.05-1.59; p = 0.038).

  Effect

  Harmful

  Effect size

  Small

  Significant

  Yes

  Dose

  100 mg once daily for 28 days