Effect of vitamin C and hesperidin on serum uric acid concentrations in healthy adults with high uric acid levels: the randomized controlled 'HesperidrinC trial'.
- 2026-02-25
- RCT · n = 40
- European journal of nutrition 65(2)
- Janna Enderle
- Rebecca Dörner
- Daria Tondar
- Mario Hasler
- Caroline Gilcher
- Christof B Steingass
- Ralf Schweiggert
- Manfred J Müller
- Anja Bosy-Westphal
- PubMed: 41739218
- DOI: 10.1007/s00394-026-03905-z
- High evidence
- Rigorous Journal
- Clinical
Levels of SUA decreased in response to VitC and VitC+Hesp with no changes in urinary uric acid excretion (UUA) or clearance (UAC).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 240 mg/day