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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Hesperidin and Reduced Blood Cholesterol

Doses used in studies

mg/day: 500 (median 500, IQR 500–500) — 1 study

2 of 2 papersPopulation:

Effect of hesperidin on blood pressure and lipid profile: A systematic review and meta-analysis of randomized controlled trials.
- 2024-03-10
- Meta-Analysis · n = 2,414
- Phytotherapy research : PTR 38(5)
- - Hanumanthappa Shylaja
  - Gollapalle Lakshminarayanashastry Viswanatha
  - Venkategowda Sunil
  - Shalam M Hussain
  - Syeda Ayesha Farhana
- PubMed: 38462779
- DOI: 10.1002/ptr.8174
6 Insights on
- Reduced Blood Cholesterol
- High evidence
- Clinical
hesperidin has significantly reduced ... total cholesterol (TC) (IV: -61 (-0.82 to -0.41) at 95% CI, p < 0.00001, I² = 69%)
Effect
Beneficial
Effect size
Large
Significant
Yes
Effects of Hesperidin Supplementation on Cardiometabolic Markers: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
- 2024-07-22
- Meta-Analysis
- Nutrition reviews 83(3)
- - Zeinab Heidari
  - Fatemeh Farahmandpour
  - Hadi Bazyar
  - Fereshteh Pashayee-Khamene
- PubMed: 39038797
- DOI: 10.1093/nutrit/nuae084
6 Insights on
- Reduced Blood Cholesterol
- High evidence
- Adults
hesperidin supplementation had a significant impact on reducing TC
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
exceeding 500 mg/day