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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Konjac and Reduced 2-Hour Postprandial Blood Glucose

Doses used in studies

g/day: 60 (median 60, IQR 60–60) — 1 study

Time to effect

Median: 3 months · IQR 3 months–3 months · Range 3 months–3 months — Reported in 1 of 2 studies

Safety in these studies

increased anal flatulenceReported
one case reported increased anal flatulence
from: [The Effect of Konjac Glucomannan on Blood Glucose and Insulin Levels in Obese Patients Wi
severe abdominal discomfortReported
two participants in the KGM group experienced severe abdominal discomfort, which resolved after discontinuing the biscuits
from: [The Effect of Konjac Glucomannan on Blood Glucose and Insulin Levels in Obese Patients Wi
transient diarrheaReported
two cases reported transient diarrhea
from: [The Effect of Konjac Glucomannan on Blood Glucose and Insulin Levels in Obese Patients Wi

2 of 2 papers

Effects of Glucomannan Supplementation on Type II Diabetes Mellitus in Humans: A Meta-Analysis.
- 2023-01-24
- Meta-Analysis · n = 440
- Nutrients 15(3)
- - Zhanzhi Zhang
  - Yu Zhang
  - Xiaomei Tao
  - Yuying Wang
  - Benqiang Rao
  - Hanping Shi
- PubMed: 36771306
- DOI: 10.3390/nu15030601
6 Insights on
- Reduced 2-Hour Postprandial Blood Glucose
- High evidence
- Rigorous Journal
- Clinical
2 h postprandial blood glucose (P2hBG) (MD -1.92 [95% CI: -3.19, -0.65], p = 0.003)
Effect
Beneficial
Effect size
Large
Significant
Yes
[The Effect of Konjac Glucomannan on Blood Glucose and Insulin Levels in Obese Patients With Prediabetes].
- 2026-05-01
- RCT · n = 102
- Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 57(3)
- - Renhua Wu
  - Lirui Tang
  - Xiaoling Yang
  - Qing Ou
  - Yan Gu
  - Li Yuan
  - Nanwei Tong
- PubMed: 42369710
- DOI: 10.12182/20260560508
10 Insights on
- Reduced 2-Hour Postprandial Blood Glucose
- High evidence
- Large Human Trial
- Clinical
However, there were no statistically significant differences between the two groups in body mass index, 2-hour postprandial blood glucose, 2-hour postprandial insulin, or effective control of pancreatic β-cell activity (P > 0.05).
Effect
Neutral
Effect size
Small
Significant
No
Dose
60 g of konjac-based dietary fiber biscuits daily