Efficacy of Olive Leaf Extract in Improving Blood Pressure in Pre-Hypertensive and Hypertensive Individuals: A Systematic Review and Meta-Analysis.
- 2025-05-05
- Review · n = 248
- Phytotherapy research : PTR 39(6)
- Rebeca Lachovicz
- Vera Ferro-Lebres
- Juliana Almeida-de-Souza
- José Alberto Pereira
- PubMed: 40325976
- DOI: 10.1002/ptr.8509
- High evidence
- Clinical
An antihypertensive effect was observed on systolic and diastolic blood pressure in the pre- vs. post-intervention in the global analysis (systolic -6.03 mmHg, 95% CI: [-11.60, -0.46], I² = 82%, p = 0.03) and in the sub-analysis that included the studies with the highest dose (1000 mg/day) (systolic -11.45 mmHg, 95% CI:[-13.99, -8.91], I² = 0%, p ≤ 0.001).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- varied (highest dose 1000 mg/day analysed in sub-analysis)