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Evidence-Based Supplement Research
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Pine

Safety profile

6 studies reporting safety data

Across 6 clinical studies, no adverse events were found to be significantly increased compared to control. One study reported no significant difference in side effect rates between groups, while 11 general tolerability mentions described pine as well tolerated, with mild and transient events such as gastrointestinal problems, headache, and nausea. The substance was consistently associated with a favorable safety profile, though quantitative safety data were limited.

Caveats: Evidence is limited to short-term studies; long-term safety not established. Most studies were not primarily designed to assess safety, so rare adverse events may not have been detected.

Most-studied combinations with Pine

most supplement research is combination research
Also studied with:Lemon Balm (2), Olive (2), Ginkgo (2), Ginseng (2)

  • Policosanol

    By NOW Foods

    4.6 (371 reviews)
    Out of Stock
    Available From
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    Amazon
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    iHerb
    $21.42
    		In
    Vitacost
    $19.89
    		In
    Vitamin Shoppe
    $-
    		Out

  • Enzogenol Pine Bark Extract

    By ProHealth Longevity

    4.8 (8 reviews)
    Out of Stock
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    iHerb
    $49.95
    		In
    Vitacost
    $-
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    Vitamin Shoppe
    $-
    		Out

  • Test X180 Alpha V2

    By Force Factor

    4.7 (22 reviews)
    In Stock
    Available From
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    Amazon
    $-
    		Out
    iHerb
    $44.99
    		In
    Vitacost
    $-
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    Vitamin Shoppe
    $-
    		Out

  • French-Maritime Pycnogenol

    By Viva Naturals

    4.9 (196 reviews)
    In Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    		Out
    iHerb
    $60.63
    		In
    Vitacost
    $-
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    Vitamin Shoppe
    $-
    		Out

  • Organic Pine Bark Extract with OPCs

    By Dr. Mercola

    4.7 (12 reviews)
    Out of Stock
    Available From
    Available From
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    Amazon
    $-
    		Out
    iHerb
    $43.97
    		In
    Vitacost
    $-
    		Out
    Vitamin Shoppe
    $-
    		Out

  • Pycnogenol

    By Natrol

    4.6 (175 reviews)
    In Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    		Out
    iHerb
    $38.58
    		In
    Vitacost
    $37.89
    		In
    Vitamin Shoppe
    $-
    		Out
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