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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Pine

Safety profile

4 studies reporting safety data

Across 4 clinical studies, no specific adverse events showed increased risk or significant differences compared to control. Pine bark extract was generally described as well tolerated in multiple studies, with mild side effects noted in some cases. One study reported a reduction in gastric complications associated with pine bark extract supplementation in osteoarthritis patients.

Caveats: Limited evidence base (4 studies); absence of quantitative safety data does not establish safety. Most studies were not primarily designed to assess safety, and long-term or population-specific safety is not characterized.

Most-studied combinations with Pine

most supplement research is combination research
Also studied with:Lemon Balm (2), Ginkgo (2), Ginseng (2)

  • Policosanol

    By NOW Foods

    4.6 (371 reviews)
    Out of Stock
    Available From
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    MerchantPriceStockAction
    Amazon
    $-
    		Out
    iHerb
    $21.42
    		In
    Vitacost
    $19.89
    		In
    Vitamin Shoppe
    $-
    		Out

  • Enzogenol Pine Bark Extract

    By ProHealth Longevity

    4.8 (8 reviews)
    Out of Stock
    Available From
    Available From
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    Amazon
    $-
    		Out
    iHerb
    $49.95
    		In
    Vitacost
    $-
    		Out
    Vitamin Shoppe
    $-
    		Out

  • Test X180 Alpha V2

    By Force Factor

    4.7 (22 reviews)
    In Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    		Out
    iHerb
    $44.99
    		In
    Vitacost
    $-
    		Out
    Vitamin Shoppe
    $-
    		Out

  • French-Maritime Pycnogenol

    By Viva Naturals

    4.9 (196 reviews)
    In Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    		Out
    iHerb
    $60.63
    		In
    Vitacost
    $-
    		Out
    Vitamin Shoppe
    $-
    		Out

  • Organic Pine Bark Extract with OPCs

    By Dr. Mercola

    4.7 (12 reviews)
    Out of Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    		Out
    iHerb
    $43.97
    		In
    Vitacost
    $-
    		Out
    Vitamin Shoppe
    $-
    		Out

  • Pycnogenol

    By Natrol

    4.6 (175 reviews)
    In Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    		Out
    iHerb
    $38.58
    		In
    Vitacost
    $37.89
    		In
    Vitamin Shoppe
    $-
    		Out
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