Polypodium Leucotomos and Reduced Oral Antihistamine Use

• Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial.

  • 2012-09
  • RCT · n = 105
  • Actas dermo-sifiliograficas 103(7)
  • • A Ramírez-Bosca
    • P Zapater
    • I Betlloch
    • F Albero
    • A Martínez
    • J Díaz-Alperi
    • J F Horga

  • PubMed: 22560125
  • DOI: 10.1016/j.ad.2012.01.008

  2 Insights on

  • Reduced Oral Antihistamine Use

  • High evidence
  • Large Human Trial
  • Clinical

  A significant reduction was, however, observed for oral histamine use (median percentage of days, 4.5% in the Polypodium leucotomos group and 13.6% in the placebo group [P= .038]).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes