Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Pomegranate and Reduced Systolic Blood Pressure

Doses used in studies

g/day: 50 (median 50, IQR 50–50) — 1 study
mg/day: 740 (median 740, IQR 740–740) — 1 study

Time to effect

Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Effects of Pomegranate Extract on Inflammatory Markers and Cardiometabolic Risk Factors in Adults Aged 55-70 Years: A Randomised Controlled Parallel Trial.
- 2025-04-01
- RCT · n = 86
- Nutrients 17(7)
- - Grace Farhat
  - Jhama Malla
  - Jay Vadher
  - Emad A S Al-Dujaili
- PubMed: 40218993
- DOI: 10.3390/nu17071235
6 Insights on
- Reduced Systolic Blood Pressure
- High evidence
- Rigorous Journal
- Elderly
Systolic blood pressure significantly decreased in the PE group (by 5.22 ± 1.26 mmHg (SE), p = 0.04), indicating potential clinical relevance
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
740 mg/day
Acute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial.
- 2026-03
- RCT
- The Journal of nutrition 156(3)
- - Manal M Almoraie
  - Jeremy Pe Spencer
  - Carol Wagstaff
  - Kim G Jackson
- PubMed: 41580088
- DOI: 10.1016/j.tjnut.2026.101374
6 Insights on
- Reduced Systolic Blood Pressure
- High evidence
- Mixed
systolic BP lower after the PSO-rich meal than the control meal
Effect
Beneficial
Effect size
Small
Dose
50 g fat mixed meal enriched with pomegranate seed oil (80% conjugated α-linolenic acids)