Gastric cooling and menthol cause an increase in cardiac parasympathetic efferent activity in healthy adult human volunteers.
- 2018-08-19
- RCT
- Experimental physiology 103(10)
- Lubobo-Claude Kazadi
- Janine Fletcher
- Paul A Barrow
- PubMed: 30070742
- DOI: 10.1113/ep087058
- High evidence
- Adults
The additional effect of gastric cold stimulation was significantly to reduce heart rate for up to 15 min, elevate indicators of cardiac parasympathetic tone and eliminate the reduction in QTc interval seen with gastric stretch only.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 300 ml of solution at 6°C